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KMID : 0614620230810040173
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Korean Journal of Gastroenterology
2023 Volume.81 No. 4 p.173 ~ p.177
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First Case of Atypical, Generalized Skin Rash after Transarterial Chemoembolization in a Patient with Hepatocellular Carcinoma
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Lee Yo-Han
Cho Eun-Ae
Park Chang-Hwan
Yoon Jae-Hyun
Choi Sung-Kyu
Kim Hyoung-Ook
Park Chan
Yun Sook-Jung
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Abstract
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Transarterial chemoembolization (TACE) is a widely used hepatocellular carcinoma (HCC) treatment. Some cases of supraumbilical skin rash after TACE in patients with HCC have been reported. To the best of the authors’ knowledge, there are no reports on atypical, generalized rashes caused by doxorubicin systemic absorption after TACE. This paper presents the case of a 64-year-old male with HCC who developed generalized macules and patches one day after a successful TACE procedure. A histology examination of a skin biopsy of a dark reddish patch on the knee revealed severe interface dermatitis. He was treated with a topical steroid, and all skin rashes improved within a week with no side effects. This report presents this rare case with a literature review on skin rash after TACE.
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KEYWORD
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Carcinoma, hepatocellular, Drug-related side effects and adverse reactions, Exanthema, Chemoembolization, therapeutic
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